About 1Day Sooner
1Day Sooner is a nonprofit that advocates for people who participate and want to participate in high-impact medical studies, particularly human challenge trials, where healthy volunteers are infected with a disease to test a vaccine, treatment, or to learn other important information.
In line with the altruism of healthy volunteers, we more broadly work towards a world that prioritizes efficient development of life-saving medical research, distributed equitably so as to minimize the global suffering caused by infectious disease.
We organize volunteers who are in studies and people who want to be in studies; we engage in advocacy with regulators, lawmakers, and other stakeholders globally; we support and conduct research on vaccines policy, biosecurity, public health, and research ethics; and we assist in communications and outreach to elevate the voices of healthy volunteers in public discourse.
Challenge study support & advocacy
We have worked with high-impact medical studies, including human challenge studies in the United States, Australia, Canada, and the United Kingdom. This has included pro-bono assistance with publicity, consulting on and aiding in advertising and recruitment efforts, and advising on ethical study design.
For our volunteers, we provide social and moral support if they choose to sign up for a study.
Hepatitis C Human Challenge Study Development
Tens of millions of people are infected with hepatitis C, but there is no vaccine. We, like a a growing number of researchers in the field, believe that human challenge studies are the only realistic way to test potential vaccines in the foreseeable future. Since 2021, we have worked closely with specialists around the world putting together proposals for the first ever hepatitis C challenge studies.
AMCs & Operation Warp Speed 2
UK Pandemic Preparedness Policy
The United Kingdom spearheaded challenge studies for COVID-19, and we are pushing to institutionalize the lessons learned when it comes to challenge trials in the face of a pandemic with the UK Pandemic Ethics Accelerator. Research and events supporting the implementation of our recommendations are forthcoming.
Indoor Air Quality
Global Health Equity
1Day Sooner was founded in March 2020 to represent challenge volunteers who wanted to accelerate the deployment of the most effective COVID-19 vaccines possible.
Over 38,000 people signed up with us, expressing their desire to volunteer for a human challenge trials that could have possibly done so. In 2020, 1Day Sooner built a robust volunteer community and drew significant global public attention to the potential of human challenge trials, with the altruism of volunteers at the forefront of stories.
1Day Sooner has since expanded to work in other types of challenge studies and on other projects such as pandemic preparedness policy and vaccine equity.
Meet 1Day Volunteers
Become a Volunteer
1Day Sooner tracks clinical research for a variety of infectious diseases and sends information to our volunteers if a study begins recruiting near them. We focus on studies with higher potential to save lives, including studies related to vaccine development, neglected diseases, and diseases that represent possible future pandemic threats.