Highlights
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April 2025
Unearthing the FDA’s Treasure Trove: Using AI to Revolutionize Drug Development

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March 25, 2025
A faster rollout of malaria vaccines would save many lives

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December 19, 2024
The future of pandemic preparedness with Josh Morrison

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January 17, 2024
Ultraviolet light can kill almost all the viruses in a room. Why isn’t it everywhere?
by Vox

Latest 1Day Sooner Media Mentions
2026
July 16: Healthy Debate: Canada must take the lead on hepatitis C vaccine research.
June 22: Springer Nature Research Communities: The HIT Study: towards a Hepatitis C controlled human infection model.
June 8: Clinical Leader: The FDA Could Clear The Path For A Strep A Vaccine. Why Hasn’t It?
May 20: American Affairs: Invisible Infrastructure, Visible Results: A Conservative Case for Clean Indoor Air
April 30: The Star: Nairobi declaration calls for urgent action on health security in Africa
2025
October 22: STAT First Opinion podcast: Would you contract dysentery for $7,300?
October 10: Chemical & Engineering News: How do drug trials really work? I got dengue fever to find out
October 8: City Journal: HHS Should Expand Access to Health Data
September 25: A Shot at History (Fix the News podcast): The Jab
September 18: Works in Progress: The death rays that guard life
September 17: Africa Science: New African model launches early-phase clinical trial support for infectious disease research
September 16: PRIMR Research Ethics Imagined podcast: Human Challenge Studies with Wilbur H. Chen, MD and Jake Eberts
September 15: A Shot at History (Fix the News podcast): The Chain
September 5: A Shot at History (Fix the News podcast): The Stakes
August 29: Research Ethics Imagined podcast: Human Challenge Studies with Wilbur H. Chen, MD and Jake Eberts
August 1: Clinical Leader: Why Are We So Afraid To Pay Research Participants?
July 17: STAT: Medical research participants deserve to be paid well
June 10: Nature: Not all clinical data in the United States are fragmented
May 21: Daily Nation: Lingering hurdles in malaria elimination efforts and how to win the war
May 10: Punch Nigeria: Africa malaria vaccine rollout delays must be addressed
April 2025: DIA Global Forum: Unearthing the FDA’s Treasure Trove: Using AI to Revolutionize Drug Development
April 29: Amref Health Africa: A Malaria-Free Africa: How Vaccines and Innovation Can Turn the Tide
April 26: Business Ghana: Calls for Urgent Action to Address Delays in Africa’s Malaria Vaccine Rollout on World Malaria Day
April 17: GCBR Organization Updates: April 2025
March 25: The Economist: A faster rollout of malaria vaccines could save many lives
March 15: Business Daily Africa: Delayed malaria vaccine rollout a costly gamble
February 28: City Journal: What to Expect from Trump’s Pick to Lead the FDA
February 7: Astral Codex Ten: 1Day Sooner’s Trump II Health Policy Proposals
February 7: El Heraldo: Se enferman voluntariamente para desarrollo de vacunas
February 3: At the Crossing podcast: Vaccine Development with Josh Morrison
January 28: The New York Times: Would You Get Sick in the Name of Science?
January 28: News Ghana: Urgent Call to Bridge $4 Billion Gap for Malaria Vaccine Rollout Across Africa
January 26: Asimov Press: The Quest for Universal Flu Vaccines
January 21: Vox: The frustrating reason we’re not saving more kids from malaria
January 7: Politico: World View
January 1: Astral Codex Ten: H5N1: Much More Than You Wanted To Know
2024
December 19: Complex Systems with Patrick McKenzie podcast: The future of pandemic preparedness, with Joshua Morrison
December 16: Center for Global Development blog: Malaria Vaccines: Turning a Scientific Triumph into Millions of Lives Saved
December 6: Politico: Marks: Mandates ‘just don’t work’ in U.S.
December 3: Vox: I got malaria on purpose and so can you
October 21: Baltimore Sun: We must prepare for hidden threats of disease from natural disasters
August 16: Cautionary Tales with Tim Harford podcast: The Human Guinea Pigs of Camp Lazear
July 21: Human Progress Doomslayer: Weekly Progress Roundup
July 6: Vox: The most crucial part of next year’s federal budget
June 1: Slow Boring: Africa needs malaria vaccines as soon as possible
May 29: 80,000 Hours Podcast: Rachel Glennerster on how “market shaping” could help solve climate change, pandemics, and other global problems
May 16: Hopkins Bloomberg Public Health: How Human Challenge Trials Accelerate Vaccine Development
May 4: Channel News Asia: What prompts people to deliberately expose themselves to an infection?
May 1: Behavioural Economics and Policy for Pandemics: Insights from Responses to COVID-19
April 22: devex: Why the silence on the shortfall in malaria vaccine doses?
April 11: Works in Progress: Should you infect yourself with Zika?
March 5: Dartmouth: Investing in a Universal COVID-19 Vaccine Would Be Worth It
February 16: Works in Progress: Life in the Time of Zika
February 14: Engineered for Impact Podcast: Improving Indoor Air Quality with Gavriel Kleinwaks
February 13: Daily Maverick: Malaria vaccine shortfall, heavy cost of Africa’s child deaths all thanks to global complacency
January 17: Vox: Ultraviolet light can kill almost all the viruses in a room. Why isn’t it everywhere?
January 3: The New York Times: Millions Die of Malaria With Miracle Drugs at Hand
2023
November 9: The Minnesota Daily: Preparing for the next pandemic
November 3: Vox: Malawi scientists have a plan to fight one of their country’s biggest killers
October 20 : Vox: Josh Morrison took risks for science, and he thinks you can, too
June 27: National Geographic: In the UK, Young adults are volunteering to get COVID-19—for science
May 8: The Wire India: Should the First COVID Human Challenge Trial Also Be the Last?
April 22: CJ Online: Operation Warp Speed 2.0?
April 7: Swarthmore Phoenix: Effective Altruism: Solving Global Dilemmas One Step at a Time
January 18: Vancouver Sun: Universal vaccine only way to put coronavirus pandemics behind us for good
2022
December 29: To Vima: Εθελοντές – πειραματόζωα στην υπηρεσία της επιστήμης
December 19: BNN Breaking: Malaria Fight Slows: Over 120M Vaccine Doses Possible, Only a Fraction to be Used
December 11: Project Syndicate: A Bargain in Saving Lives
December 8: Foreign Policy: Breakthrough Malaria Vaccines Could Save Children’s Lives
November 25: Nature: These volunteers want to be infected with disease to aid research – will their altruism help?
August 25: The Hindu: Battling a deliberately-acquired infection to help find a cure
April 6: Clinical Trials Arena: Disease X — UK releases a blueprint on pandemic human challenge trials
April 5: Reason: I Gave Myself Severe Diarrhea for Science. Don’t Tax Me for It.
March 30: STAT News: To deal with the next pandemic, the FDA needs an Office of Preparedness and Response
March 13: Hopkins Bloomberg Public Health: How Human Challenge Trials Accelerate Vaccine Development
March 11: Freethink: Volunteers were purposefully infected with COVID-19. Was it worth it?
2021
December 22: Der Spiegel: Geimpft – und ausgesperrt
December 1: Business Ghana: West African Nations Bring Proposal for a Pandemic Insurance Fund to the World Health Assembly
December 1: Pan African Visions: West African Nations Bring Proposal for a Pandemic Insurance Fund to the World Health Assembly
November 4: Boston Globe: With COVID-19 vaccine for younger children, a chance to promote health equity across all ages
November 3: Pan African Visions: African Frontline Healthcare Workers Need More Support
November 3: Punch: African frontline healthcare workers need more support
October 14: New York Times: Britain Infected Volunteers With the Coronavirus. Why Won’t the U.S.?
September 23: Harvard University: Finding community in Boston Vaccine Day
September 19: iHeart Radio: Boston Vaccine Day Held In Roxbury
September 18: Boston Globe: ‘You can’t miss this message.’ Roxbury hosts Boston Vaccine Day in an effort to promote shots against COVID-19
September 14: Boston Globe: Boston Vaccine Day is an inoculation celebration
September 11: The Economist: Why scientists are deliberately infecting volunteers with covid-19
September 4: The Wall Street Journal: Researchers Infect Volunteers With Coronavirus, Hoping to Conquer Covid-19
September 3: Wall Street Journal: The Man Who Chose to Get Covid
September 2: Marie Claire: Coronavirus Vaccine: ‘I recruited people to be deliberately infected with Covid-19’
June 23: The New Dawn: Doctor Fallah to speak at a congressional briefing
June 1: The Guardian: Human challenge: the people volunteering to be infected with Covid
March 31: Vox: What kind of person signs up to be infected with the coronavirus on purpose?
March 24: The Guardian: Covid trial infecting healthy volunteers needs full transparency, say campaigners
March 18: Boston Globe: Faster vaccine trials could save lives without sacrificing ethics
March 16: Bloomberg: How ‘Vaccine Day’ Could Boost Inoculations
March 10: WRTV: Some pushing for one-time federal holiday called ‘National Vaccine Day’
March 10: Good Morning America: Former US surgeon general calls for National Vaccine Day
March 2: ABC: 4 former surgeons general join call for ‘National Vaccine Day’
February 22: British Medical Journal: Sixty seconds on . . . human challenge trials
February 17: Financial Times: World’s first trial of deliberate coronavirus infection is approved
February 17: The Times: Scientists win approval to infect healthy volunteers with Covid for trial
February 17: Wired: The UK is infecting people with Covid-19 for science. Is it worth it?
February 17: Wall Street Journal: U.K. Approves Trials That Will Deliberately Infect Volunteers With Coronavirus
February 17: The New York Times: U.K. Approves Study That Will Deliberately Infect Volunteers With Coronavirus
February 7: News Medical: Healthy people volunteering to be infected with SARS-CoV-2 should be paid, experts suggest
January 20: Slow Boring: The case for vaccine challenge trials
January 8: British Medical Journal: Human challenge trials of covid-19 vaccines still have much to teach us
2020
December 26: New York Post: Britain will be first to infect healthy volunteers with COVID-19 for research
December 16: Smithsonian: A Brief History of Human Challenge Trials
December 11: Health Affairs: COVID-19 Challenge Trials Would Save Lives And Avert Years In Poverty By Significant Margins
December 10: First Post: COVID-19 vaccine: Study discusses ethical dilemmas, risks in upcoming UK human challenge trials
December 9: Rutgers News: The Ethics of Human Challenge Trials
December 7: The Guardian: WHO looks at giving Covid-19 to healthy people to speed up vaccine trials
November 30: News Medical: What are the risks associated with human challenge trials for SARS-CoV-2 vaccine candidates?
November 25: TEDxWomen2020: How COVID-19 human challenge trials work— and why I volunteered
November 24: Radiolab: Dispatch 13: Challenge Trials
November 13: Varsity UK: The first COVID-19 ‘human challenge’ studies may take place in the UK
November 10: CBC: Meet the people who want to be infected with COVID-19
November 5: CNN: Why volunteers in London are deliberately being infected with COVID-19
October 30: The Lancet: COVID-19 human challenge studies in the UK
October 20: BBC: UK plan to be first to run human challenge Covid trials
October 20: Nature: Dozens to be deliberately infected with coronavirus in UK ‘human challenge’ trials
October 20: Washington Post: Britain to infect healthy volunteers with coronavirus in vaccine challenge trials
October 20: The Guardian: The volunteers lining up for Covid-19 challenge trials
October 14: The Guardian: Nobel laureates call on UK to back infecting volunteers with Covid for vaccine trials
October 14: Reason: Public Opinion Supports Covid Vaccine Challenge Trials
October 12: CNN: Most people try to avoid Covid-19. But thousands are signing up to be deliberately exposed
October 8: The Scientist: A Challenge Trial for COVID-19 Would Not Be the First of Its Kind
October 6: Washington Post: Human volunteers can help ensure we have an effective vaccine more quickly
October 2: HIC-Vac: Human challenge studies with coronavirus: towards effective vaccines
October 1: La Presse: S’infecter délibérément pour la science
September 30: GAVI: How do vaccine clinical trials ensure the benefits outweigh the risks?
September 26: The Hindu: ‘Human challenge trials will help us design better treatments, vaccines than we can now’
September 25: Financial Times: Human challenge trials bring a vaccine a step closer
September 23: BBC: Covid-19: UK volunteers could be given virus to test vaccine
September 23: CNN: UK mulling vaccine trials that deliberately expose volunteers to Covid-19
September 23: Reuters: UK to host ‘human challenge’ trials for COVID-19 vaccines
September 23: Financial Times: UK to test vaccines on volunteers deliberately infected with Covid-19
September 23: Telegraph: ‘Challenge trials’ set to infect volunteers with coronavirus to help speed up creation of vaccine
September 23: The Times: Britain to run first coronavirus vaccine trials that infect volunteers
September 22: WKRC: You can volunteer to be infected with COVID-19
September 21: CBS Boston: College Student Volunteers For Controversial ‘Human Challenge’ Trial For COVID-19 Vaccine
September 16: National Geographic: To find a vaccine for COVID-19, will we have to deliberately infect people?
September 15: Genetic Literacy Project: ‘Challenge studies’: Should we be testing COVID vaccines by intentionally infecting volunteers?
September 11: Men’s Health: Why I’m Risking My Life to Take Part in the COVID-19 Vaccine Trials
September 10: CTV: Would Canadians volunteer to be infected with COVID-19 to test vaccines?
September 9: Duke Research Blog: “Do No Harm to Whom?” Challenge Trials & COVID-19
September 5: Arizona Daily Star: Why I am volunteering to be infected with the coronavirus
September 2: Reason: Let Volunteers Expose Themselves to COVID-19 To Speed Up a Vaccine
September 1: Spectrum News 1: Nearly 37,000 People Have Signed up to Be Part of a COVID-19 Vaccine Trial
August 27: Castanet: Conor Barnes pre-volunteers to be infected with COVID-19, test vaccines
August 24: Toronto Star: It is worth the risk to accelerate COVID-19 vaccine testing
August 24: MTL Blog: A 27-Year-Old Quebecer Is Volunteering To Be Deliberately Exposed To The Novel Coronavirus
August 22: BBC: Challenge trials: The volunteers offering to be infected with coronavirus
August 17: The Conversation: The ethical case for allowing medical trials that deliberately infect humans with COVID-19
August 17: ABC San Francisco: What is COVID-19 human challenge testing? Doctors explain how it works
August 14: Washington Post: U.S. will prepare coronavirus strain for potential human challenge trials
August 14: Al Jazeera: US eyes controversial human challenge trials for COVID-19 vaccine
August 12: Vox: Why people are volunteering to get Covid-19
August 11: Reuters: J&J eyes one billion doses of potential COVID-19 shot in 2021, weighs challenge trials
August 10: The Telegraph: Scientists have to take risks to secure a vaccine
August 8: CBS Inside Edition: Thousands to Be Infected With COVID-19 in Controversial ‘Human Challenge’ Trials for Coronavirus Vaccine
August 7: Medscape: Are Human Challenge Trials for COVID-19 Vaccine Worth the Risk?
August 6: FiveThirtyEight: Some Volunteers Want To Be Infected With Coronavirus To Help Find A Vaccine. But It Isn’t That Simple.
August 6: NBC: Inside Oxford’s push for ‘challenge trials’ amid race for coronavirus vaccine
July 31: South China Morning Post: Vaccine race: ‘unprecedented’ momentum and questions for deliberately infecting volunteers with Covid-19
July 29: Elemental: One Man’s Quest to Infect People With Covid-19 for Science
July 29: Fox 5 Atlanta: Young volunteers willing to take ‘calculated risk’ in human challenge vaccine trials
July 20: Science Magazine: Controversial ‘human challenge’ trials for COVID-19 vaccines gain support
July 20: National Post: Support grows for deliberately exposing vaccine trial subjects to COVID-19, with Oxford team leading the way
July 19: The Print: What are human challenge trials — the experiment Oxford is considering for its Covid vaccine
July 16: Boston Globe: Scores of academics call for ‘human challenge’ trials of coronavirus vaccine
July 16: The Telegraph: Oxford coronavirus vaccine ‘challenge’ trials set to begin later this year
July 16: OC Register: Why an All-American pole vaulter wants to be exposed to coronavirus
July 16: The Guardian: Coronavirus vaccine: Oxford team aim to start lab-controlled human trials
July 16: CNN: Nobel laureates call for ‘challenge trials’ to speed up vaccine process
July 16: The Hill: Scientists ask for volunteers to be infected with coronavirus to speed vaccine development
July 15: American Medical Association: Top ethicist makes the case for COVID-19 vaccine challenge trials
July 10: NBC San Diego: COVID-19 Human Challenge Trials
July 7: USA Today: Race for a coronavirus vaccine: Why I volunteered to be exposed to COVID-19
July 6: Los Angeles Times: Young San Diegans willing to be exposed to coronavirus to help with vaccine trials
July 1: The New York Times: Researchers Debate Infecting People on Purpose to Test Coronavirus Vaccines
June 23: CBS New York: Human Challenge Trials: Thousands Of Young People Ready To Expose Themselves To Coronavirus To Find Cure
June 18: Fred Hutchinson: Scientists ponder human challenge trials for COVID-19 vaccines
June 15: PBS NewsHour: Meet people volunteering to be exposed to COVID-19 for vaccine research
June 15: Washington Post: Volunteers sign up to put their lives on the line for a coronavirus vaccine
June 15: Daily Mail: Would you volunteer to be infected with Covid-19?
June 12: Inverse Magazine: Human Volunteers Explain Why They’re Ready to Get Covid-19 On Purpose
June 11: CBS: Thousands volunteer to be exposed to coronavirus for research
May 30: Independent: ‘It’s about saving lives’ – the Irish volunteers who want to be infected with Covid-19
May 27: Reason: The Moral Case for Testing Coronavirus Vaccines through “Challenge Trials” on Paid Healthy Volunteers
May 24: Bloomberg: Volunteers Are Lining Up to Be Infected With the Coronavirus
May 23: Wired: Should we deliberately infect healthy volunteers with Covid-19?
May 22: New Yorker Radio Hour: To Test a Vaccine for COVID-19, Should Volunteers Risk their Lives?
May 22: NBC: Thousands volunteer to be infected for science
May 20: The Hill: Thousands have volunteered to be infected with coronavirus. But will that fast-track a vaccine?
May 13: CNN: Thousands of people want to be exposed to Covid-19 for science
May 11: Wall Street Journal: One Idea for Speeding a Coronavirus Vaccine: Deliberately Infecting People
May 10: NBC: Why have 14,000 people volunteered to be infected with coronavirus?
May 7: South China Morning Post: Infecting volunteers with Covid-19 may speed up coronavirus vaccine studies, WHO says
May 5: Bloomberg: Why I Just Volunteered for a Covid-19 Vaccine Trial
April 27: ABC: Injecting healthy adults with live coronavirus provides moral dilemma, faster path to vaccine
April 24: Der Spiegel: Would you volunteer to be infected with Corona?
April 23: Al Jazeera: Coronavirus: Hundreds willing to be infected for vaccine trials
April 22: MIT Tech Review: Would you volunteer to get the coronavirus?
April 22: Nature: Hundreds of people volunteer to be infected with coronavirus
April 21: The Atlantic: Let Volunteers Take the COVID Challenge

