1Day Volunteers

Below are healthy volunteers affiliated with 1Day Sooner from previous medical studies, including human challenge trials and phase I vaccine trials.

Mallory Admire

USA

Shigella flexneri 2a SF2a-TT15 vaccine challenge, 2022

“Nobody wants to get sick (especially with infectious diseases like dysentery!) but I’m hopeful that by people like me volunteering for human challenge studies, medical advances can be made to help protect those most vulnerable.”

Dominique Meyer

USA

Shigella flexneri 2a SF2a-TT15 vaccine challenge, 2022

“Medical research is very important to me from both a professional and personal standpoint. Participating in a challenge study was a great way to support research in a different way that I hope can provide a broad clinical impact and improve global health outcomes.”

Thomas A. Smiley

USA

Norovirus GII.4/CIN-3 characterization challenge, 2022

“I took the plunge and got infected with norovirus to help better understand the disease. To me, it was a relatively simple request: my health, temporarily, in return for scientific advancement.”

Angelique Mseteka

Malawi

Malaria (Plasmodium falciparum 7G8) challenge, 2021

Jacob Hopkins

UK

SARS-CoV-2 (Wuhan strain) challenge study, 2021 (The study’s first participant!)

“Like everyone, I just wanted to help. Looking back, I’m like, ‘Yeah, I did that!’ — I made an impact. Challenge trials show people’s readiness to help and how a single act can be huge. I’m grateful for the opportunity to take that risk.”

Paresh Patel

UK

SARS-CoV-2 (Wuhan strain) reinfection challenge study, 2021 (Paresh was the study’s first participant!)

“The deep nasal swabs and my initial fear of needles were awful!! But was a small sacrifice to hopefully enable us to combat Covid-19 better.”

Alastair Fraser-Urquhart

UK

SARS-CoV-2 (Wuhan strain) challenge study, 2021

“Challenge studies show us that there are people who are truly happy to take on physical risks to advance human knowledge and health.” (Read about Alastair’s experience in the Washington Post.)

Carolina Reid

USA

Malaria (Plasmodium falciparum NF54) GAP3KO vaccine challenge, 2018

“Participating in research has been the most fascinating way to connect to the medical world — I learn a lot every time and we make advancements towards a healthier world.”

Jake Eberts

USA

Shigella flexneri 2a SF2a-TT15 vaccine challenge, 2022; Zika virus dose-finding challenge, 2023

“I’m very proud of my participation. I traded my own health for a little while in the hopes that one day, others won’t have to suffer from dysentery — which I can say from personal experience is not a fun sickness to have!”

Reed Shafer-Ray

USA

Covid-19 VXCO-100 vaccine Phase I study, 2023

“I chose to receive an experimental Covid vaccine that could one day make vaccines cheaper, more effective, and more widely accessible. The decision to participate was easy — I would take slight inconvenience for the opportunity to save just one life, much less millions.”

Marcus Dahl

Australia

SARS-CoV-2 (Wuhan strain) reinfection challenge study, 2021

“The pandemic has been tough for everyone, so I was happy to put my hand up to help out. The research team was great, and getting involved became a good opportunity to fundraise for UNICEF’s COVAX global vaccine equity program at the same time.”

Paul Zimmer-Harwood

USA

Malaria (Plasmodium falciparum) challenge, 2018; SARS-CoV-2 (Wuhan strain) reinfection challenge study, 2021

Matt Beigel

USA

Shigella flexneri 2a SF2a-TT15 vaccine challenge, 2022; Zika virus dose-finding challenge, 2024

I like to participate in research studies, such as for dysentery and Zika, to know that I am doing what I can to better global health at an individual level. Getting to know others in my cohorts proves that even small efforts make a great impact and that we are all in it for the same end-goal, a healthier future!

Frank Williams

Malawi

Streptococcus pneumonia challenge, 2021

“It’s very important for us to take part in a fight against diseases by whatever means we can. Developing vaccines to many diseases is the greatest weapon the world can use.“

Keller Scholl

USA

Zika virus dose-finding challenge, 2023

“Human challenge trials can help us understand diseases and vaccines in ways sometimes nothing else can enable. I volunteered because I wanted to help.”